Researchers use AI to design enzymes that cut proteins at chosen sites

On October 15, Ars Technica reported that researchers used AI protein design tools to design proteases that cut specific proteins. The approach kept the catalytic core of two protease classes and replaced all the rest of the protein structure. Through tuning, the resulting enzymes cut a target protein into two parts. The report says the researchers used these designed proteases to cut a protein linked to neurological disease, showing the method's targeted cutting ability.

Written by AI from the coverage · updated 29 minutes ago

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