Stanford Nature Study: AI Designs 16 Phages from Scratch

斯坦福重磅研究登Nature！AI凭空造出前所未有蛋白质，超越AlphaGo

Stanford and Arc Institute used Evo to design 302 phage genomes; 16 infected, replicated, and lysed E. coli. Evo 2 uses StripedHyena 2 with a 1M-base context; Evo-Φ69 expanded 16–65× in 6 hours. The key issue is biosafety: one capsid protein had no known homolog in existing life.

Why it matters: HKR-H/K/R all pass: AI-made viable phage genomes, concrete 302/16/1M-bp details, and a clear biosecurity nerve. Score stays at 82 because it is still an AI+life-science paper, not a direct AI product or developer workflow update.